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Let's have a look at what is happening on the US markets in the middle of the day on Wednesday. Below you can find the top S&P500 gainers and losers in today's session.

Shares of fertility benefits company Progyny (NASDAQ:PGNY) jumped 3.1% in the morning session after JPMorgan raised its price target on the company's stock. JPMorgan increased its price target to $25 from $23, while maintaining a "Neutral" rating on the shares. This move reflects an updated model of the company's performance and prospects. The positive sentiment from JPMorgan follows similar actions from other analysts recently. For instance, Cantor Fitzgerald also raised its price objective to $28 from $26 while reissuing an "overweight" rating. Additionally, Truist Financial lifted its target price on Progyny to $27 from $24. The series of price target increases from Wall Street firms suggests a more optimistic outlook on the stock's valuation, likely boosting investor confidence.

Shares of athletic apparel company Under Armour (NYSE:UAA) jumped 3.1% in the morning session after a broader positive sentiment for the retail sector's increasing adoption of Artificial Intelligence (AI). 

Shares of speciality material and gas containment company Luxfer (NYSE:LXFR) jumped 3.7% in the pre-market session after the company's Gas Cylinders division entered a strategic partnership with Reynolds Logistics for the HyHaul project, a major hydrogen mobility initiative in the UK. 

Shares of digital advertising platform Magnite (NASDAQ:MGNI) jumped 5.4% in the after-market session after the company announced the expansion of its high-impact ad solutions with the introduction of new Pause Ads for leading streaming providers. 

Shares of search AI platform provider Elastic (NYSE:ESTC) jumped 6.9% in the morning session after investor optimism grew ahead of its second-quarter earnings report. 

Shares of cloud observability platform Dynatrace (NYSE:DT) jumped 3.1% in the morning session after investment firm Oppenheimer initiated coverage on the stock with an Outperform rating and a $65 price target. 

Shares of sport boat manufacturer MasterCraft (NASDAQ:MCFT) jumped 10% in the morning session after it reported second-quarter results that beat Wall Street's expectations for revenue and profit, though it offered a mixed outlook. 

Shares of cloud data platform provider Snowflake (NYSE:SNOW) jumped 3.5% in the morning session after investors showed optimism ahead of its second-quarter earnings report, scheduled for release after today's market close. The pre-earnings rally may be influenced by strong results from competitor MongoDB, which saw its own stock surge after a blowout report. Analysts are forecasting significant growth for Snowflake, with Wall Street expecting earnings of $0.27 per share, up from $0.18 in the year-ago period. Revenue is projected to climb 25% year-over-year to $1.09 billion. This optimism is supported by the company's history of beating earnings per share estimates in the last four consecutive quarters, and several analysts have recently reiterated positive ratings on the stock.

Shares of banking software provider nCino (NASDAQ:NCNO) jumped 17.7% in the morning session after the company reported better-than-expected second-quarter earnings and raised its full-year financial outlook. The company announced total revenues of $148.8 million for the quarter, a 12.4% increase year-over-year, which surpassed analyst estimates. More impressively, nCino's adjusted earnings per share (EPS) came in at $0.22, significantly outperforming the consensus forecast of $0.14. Looking ahead, nCino provided a bullish forecast, raising its full-year guidance. It now expects revenue between $585 million and $589 million and adjusted EPS between $0.77 and $0.80. This strong performance and optimistic outlook signaled to investors that the company's growth trajectory is robust, prompting the significant stock rally.

Shares of healthcare tech company GoodRx (NASDAQ:GDRX) jumped 3.1% in the morning session after investor enthusiasm continued following its recent partnership with Danish pharmaceutical giant Novo Nordisk. 

Shares of quantum computing company IonQ (NYSE:IONQ) jumped 4% in the morning session after B. Riley initiated coverage on the quantum computing company with a 'Buy' rating and set a $61 price target. 

Shares of footwear and accessories discount retailer Designer Brands (NYSE:DBI) jumped 4% in the morning session after the stock traded higher in sympathy with peer company PVH Corp., which reported second-quarter results that beat expectations. PVH announced that its revenue and earnings for the quarter came in above its prior guidance. Furthermore, the apparel company reaffirmed its full-year non-GAAP earnings outlook. The positive results from a significant player in the retail and apparel space likely lifted investor sentiment across the sector, benefiting shares of companies like Designer Brands.

Shares of regional banking company Eastern Bankshares (NASDAQ:EBC) jumped 3.3% in the after-market session after the company's Chief Executive Officer, Denis K. Sheahan, purchased 29,762 shares. 

Shares of medical technology company Inspire Medical Systems (NYSE:INSP) fell 3.7% in the morning session after the company announced that Chief Financial Officer Rick Buchholz will step down from his position. 

Shares of kitchenware and home goods retailer Williams-Sonoma (NYSE:WSM) jumped 3.7% in the morning session after it reported strong second-quarter 2025 financial results that surpassed analyst expectations on profitability. 

Shares of doughnut chain Krispy Kreme (NASDAQ:DNUT) fell 6.6% in the morning session after JPMorgan downgraded the stock to 'Underweight' from 'Neutral', citing significant risks in its turnaround plan. The investment bank expressed concerns about high execution risks, declining U.S. business trends, and challenges associated with refranchising multiple international assets. JPMorgan also highlighted Krispy Kreme's substantial debt, with over $1 billion in net debt compared to its equity market capitalization of roughly $650 million. The downgrade follows the company's recent wider-than-expected quarterly loss and the announcement of a new turnaround strategy. According to the brokerage, these underlying issues limit the visibility of the proposed plan's success.

Shares of healthcare data analytics company Health Catalyst (NASDAQ:HCAT) fell 4.1% in the morning session after Piper Sandler downgraded the stock's rating to Neutral from Overweight and slashed its price target in half. 

Shares of digital advertising technology company PubMatic (NASDAQ:PUBM) jumped 5.2% in the pre-market session after peer ad tech company JOYY reported strong second-quarter financial results, boosting sentiment across the sector. 

Shares of cybersecurity AI platform provider SentinelOne (NYSE:S) jumped 3.4% in the morning session after investors grew optimistic ahead of its second-quarter fiscal 2026 earnings report, scheduled for release on August 28, 2025. 

Shares of restaurant company Cracker Barrel (NASDAQ:CBRL) jumped 8.7% in the morning session after the company announced it was reversing a controversial logo rebrand following customer backlash. 

Shares of earth imaging satellite company Planet Labs (NYSE:PL) jumped 4% in the pre-market session after the company announced the successful launch of two high-resolution, AI-enabled satellites, Pelican-3 and Pelican-4. 

Shares of semiconductor photomask manufacturer Photronics (NASDAQ:PLAB) jumped 5.1% in the morning session after the company reported second-quarter 2025 earnings that surpassed analyst expectations. 

Shares of mortgage servicing company Mr. Cooper Group (NASDAQ:COOP) jumped 3.1% in the morning session after analysts reaffirmed their positive outlook on the company. 

Shares of electronic brokerage firm Interactive Brokers (NASDAQ:IBKR) fell 3.4% in the morning session after a technical pullback as the stock rallied on news of its upcoming inclusion in the S&P 500 index. 

Shares of cloud software provider Upland Software (NASDAQ:UPLD) jumped 3.2% in the morning session after an analyst at Needham upgraded the stock to Buy from Hold and set a price target of $4.50. 

Shares of smart security company Arlo (NYSE:ARLO) jumped 3.4% in the pre-market session after the company unveiled a new comprehensive lineup of AI-powered smart home security cameras. 

Shares of technology real estate company Offerpad (NYSE:OPAD) fell 5% in the morning session after the recent rally linked to a "meme" stock frenzy appeared to lose steam. The decline extends a recent pullback after shares surged over 310% in the past two months. This rally was largely fueled by retail investor excitement surrounding its competitor, Opendoor Technologies, leading many observers to label it a "meme" stock resurgence. 

Shares of infrastructure investment and operations firm FTAI Infrastructure (NASDAQ:FIP) jumped 4.9% in the pre-market session after a new SEC filing revealed that Tejara Capital Ltd has increased its position in the company. 

Shares of cloud content management platform Box (NYSE:BOX) jumped 3% in the morning session after the company reported second-quarter financial results that exceeded Wall Street expectations for revenue and profit. 

Shares of healthcare services company Agilon Health (NYSE:AGL) jumped 7.4% in the morning session after it rebound following a steep drop in the previous trading day. 

Amazon stock took a hit on AI fears but its big spending could help accelerate cloud growth next year, Morgan Stanley says.

Shares of real estate technology company The Real Brokerage (NASDAQ:REAX) jumped 4% in the morning session after the company announced that Showcase Real Estate has joined its platform through its Private Label program. 

Shares of telecommunications infrastructure company Lumen Technologies (NYSE:LUMN) jumped 4.3% in the morning session after the company announced it is teaming up with Pac-12 Enterprises to power a new era in sports broadcasting. 

Shares of packaged foods company J.M Smucker (NYSE:SJM) fell 3.7% in the morning session after the company reported disappointing second-quarter financial results that missed analyst expectations on profit. 

Shares of filtration equipment manufacturer Donaldson (NYSE:DCI) jumped 7% in the morning session after the company reported second-quarter 2025 results that surpassed analyst expectations for both revenue and earnings. 

Shares of cannabis company Tilray Brands (NASDAQ:TLRY) fell 5.8% in the morning session after investors took profits after a significant rally in the previous session. 

Shares of young adult apparel retailer American Eagle Outfitters (NYSE:AEO) jumped 5.1% in the morning session after the company announced a collaboration with NFL star tight end Travis Kelce. 

Shares of beauty products company Coty (NYSE:COTY) jumped 8.1% in the morning session after a company disclosure revealed that CEO Sue Nabi purchased $1 million worth of its stock. 

Shares of business intelligence platform Domo (NASDAQ:DOMO) jumped 8.4% in the morning session after the company announced it signed a strategic collaboration agreement with Amazon Web Services (AWS) to accelerate the adoption of generative artificial intelligence solutions. 

Shares of animal health company Elanco (NYSE:ELAN) jumped 4.4% in the morning session after the company announced it will be joining the S&P MidCap 400 index. 

Shares of devSecOps platform provider GitLab (NASDAQ:GTLB) jumped 5.4% in the morning session after the stock experienced an unusually large volume of bullish options trading. 

Shares of multinational media and entertainment corporation Paramount (NASDAQ:PARA) fell 5.7% in the morning session after analysts at Morgan Stanley and Guggenheim expressed a more cautious outlook on the media company's shares. 

Shares of 3D printing company 3D Systems (NYSE:DDD) jumped 21.4% in the morning session after the company announced it was awarded a $7.65 million contract from the U.S. Air Force. 

Shares of identity management company Okta (NASDAQ:OKTA) jumped 3.4% in the morning session after the company reported strong second-quarter earnings that surpassed analyst expectations and raised its full-year financial forecast. The identity and access management company announced adjusted earnings per share (EPS) of $0.91 on revenue of $728 million, which grew 12.7% year-over-year. These results exceeded consensus estimates of $0.85 in adjusted EPS and $711.6 million in revenue. Looking ahead, the company provided an optimistic outlook, raising its full-year guidance for both revenue and adjusted EPS. Management now expects full-year revenue of $2.88 billion and adjusted EPS of $3.36 at the midpoint. Additionally, its revenue guidance for the upcoming third quarter also surpassed Wall Street's expectations.

Shares of department store chain Kohl’s (NYSE:KSS) jumped 20% in the morning session after the company reported better-than-expected second-quarter earnings and significantly raised its annual profit forecast, signaling that its turnaround efforts may be gaining traction. 

Shares of satellite communications company EchoStar (NASDAQGS:SATS) jumped 13.6% in the morning session after the stock extended its positive momentum as the company announced a $23 billion deal to sell some of its wireless spectrum licenses to AT&T. 

Shares of cosmetics company e.l.f. Beauty (NYSE:ELF) jumped 6.7% in the morning session after strong earnings from retailer Kohl's highlighted robust consumer spending in the beauty sector.